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Konstantin G. Arbeev

Ph. Doctor

Duke University, Trent Hall, Room 002, Box 90408

Durham, NC 27708,  USA

 

Tel.: (+1) 919-668-2707

Fax: (+1) 919-684-3861

 

BIOGRAPHICAL DATA:

 

Date of Birth:            April 29, 1973

 

Citizenship:               Russia (a Lawful Permanent Resident of the United States of America since April 2006)

 

Marital Status:          married, three children

 

 

EDUCATION:

 

1999                      Ph.D. in Mathematics and Physics (emphasized in: Theoretical bases of mathematical modeling, numerical methods and programming), Ulyanovsk State University, Russia.

                                  

                             Dissertation:  [Stochastic models of markets of homogeneous assets: Strategies of optimal investment, estimation of parameters] (in Russian)

 

1995                M.S. (Master’s degree in Applied Mathematics), Moscow State University n. a. M.V. Lomonosov, Russia

 

 

ACADEMIC AND PROFESSIONAL APPOINTMENTS:

 

2006-present       research scientist, senior research scientist (since July 2008), Center for Population Health and Aging and Sociology Department, Duke University, Durham, NC, USA

 

2004-2006            research scientist, Center for Demographic Studies at Duke University, Durham, NC, USA

 

2002-2003            post-doctoral fellow at Laboratory of Advanced Statistical Methods, Max Planck Institute for Demographic

                                Research, Rostock, Germany

 

2000-2002            post-doctoral fellow at Laboratory of Survival and Longevity, Max Planck Institute for Demographic Research,

                                Rostock, Germany

 

1999-2000            guest researcher at Laboratory of Advanced Statistical Methods, Max Plank Institute of Demographic Research, Rostock, Germany

 

1999-2000            assistant professor, Department of Applied Mathematics, Ulyanovsk State University, Russia

 

1999-2000            system programmer, Department of Applied Mathematics, Ulyanovsk State University, Russia

 

1995-1999            system programmer, Department of Information Technologies,                         Incombank, Ulyanovsk, Russia

 

1995-1998            PhD student at Ulyanovsk State University (Theoretical bases of mathematical modeling, numerical methods and programming)

 

1990-1995           student at Moscow State University (branch in Ulyanovsk), Mechanical and Mathematical Faculty, Ulyanovsk, Russia

 

AWARDS:

 

2008-present   NIH/NIA grant “The future of major geriatric disorders in the US elderly” (investigator)

 

2007-present   NIH/NIA grant “Evaluating new genetic effects on health and aging from longitudinal data” (key investigator)

 

2006-present   NIH/NIA grant “Dynamic determinants of exceptional health at late ages” (key investigator)

 

2005-present   NIH/NIA grant “Healthy life at risk:  The role of senescence” (key investigator)

 

2002-2009       NIH/NIA grant Oldest old mortality: Demographic models and analysis” (key investigator)

 

2004-2005       NIH/NIA grant “Population models of factors affecting health trends” (investigator)

 

2000-2002       postdoctoral scholarship from Max Planck Society for research at the Max Planck Institute for Demographic Research, Rostock, Germany

 

2000-2001       Max Planck Society fellowship for International Max Planck Research School for Demography, Winter Semester 2000/2001

 

1999-2000       RFBR (The Russian Foundation for Basic Research) grant for “Investigation of the asymptotic behavior of the distributions of normalized multivariate processes and random walks in random environments” (investigator)

 

1998                RFH (Russian Foundation for the Humanities) grant for study in Mathematical Finance (investigator)

 

1995                Diploma of Excellence, Moscow State University (branch in Ulyanovsk)

 

COURSES TAUGHT:

 

2000                Advanced Topics in the Theory of Random Processes (Ulyanovsk State University)

1999-2000       Mathematical Statistics and Probability Theory for Economists and Sociologists (Ulyanovsk State University)

1999-2000              Financial Mathematics (Ulyanovsk State University)

1999                Mathematical Statistics (Ulyanovsk State University)

 

 

MAJOR RESEARCH PROJECTS:

 

2008-present   The future of major geriatric disorders in the US elderly

2007-present   Evaluating new genetic effects on health and aging from longitudinal data

2006-present   Dynamic determinants of exceptional health at late ages

2005-present   Healthy life at risk: The role of senescence

2002-2009       Oldest old mortality: Demographic models and analysis

2004-2005       Population models of factors affecting health trends

2002-2003       Development of mathematical and computer models of aging and mortality appropriate for the analysis of statistical data on related and unrelated individuals, data from stress experiments with laboratory subjects, as well as data from longitudinal studies of aging

2001-2002       Multivariate frailty models applied to twin data

2001-2002       Mortality surfaces in demography

2001-2002       Math models applied to cancer epidemiology

2001                Statistical methods in palaeodemography

2000-2001       Math models of individual and population aging

1999-2000       Stress and aging

1999-2000       Investigation of the asymptotic behavior of the distributions of normalized multivariate processes and random walks in random environments

1998-2000       Metabolic rate and aging in insects

1998-2000       Metabolic rate and human aging

1998-2000       Stress, heterogeneity and hormesis

1998                Mathematical finance

 

 

PROFESSIONAL MEMBERSHIPS:

 

            Member of the International Genetic Epidemiology Society (IGES)

            Member of the Population Association of America (PAA)

 

 

PAPERS REVIEWED FOR:

 

            Journal of Gerontology: Biological Sciences

            Mathematical Biosciences

            Theoretical Population Biology

            Human Genomics

 

 

RESEARCH TRAINING:

 

2000-2001              International Max Planck Research School for Demography, Winter Semester 2000/2001 (Certificates in: Formal Demography, Mathematical Modeling of Aging and Mortality, Analysis of Population Changes and Differences, and Population Forecasting)

 

 

TECHNICAL SKILLS:

 

Mathematical/Statistical: SAS, R, SPSS, Maple, Mathematica, aML (advanced event history analysis including heterogeneity models), WinBUGS (Bayesian methods), Lexis (mortality surfaces visualization), Lipro (demographic forecasts)

 

Programming: MATLAB, Python, C, C++, Pascal

 

Database Management: FoxPro, MS Access

 

Office Family Products: MS Office, Open Office

 

Text Editing and Typesetting: LaTeX

 

Operating Systems: MS-DOS, MS Windows (95, 98, 2000, NT 4.0, XP, Vista)

 

 

LANGUAGES:

 

            Russian (native)

            English (speak, read and write fluently)

            German (read and translate with vocabulary)

 

 

 

PUBLICATIONS:

1.      Arbeev K.G. (1996) [Estimation of parameters in a system of stochastic equations of diffusion type]. In: Melnikov B.F. (Ed.) “Fundamental Problems in Mathematics and Mechanics.” Ulyanovsk: ULGU, vol. 2, pp. 7-8 (in Russian).

2.      Arbeev K.G. (1997) [One algorithm of construction of optimal basis in multiply connected diffusion type systems]. In: Melnikov B.F. (Ed.) “Fundamental Problems in Mathematics and Mechanics.” Ulyanovsk: ULGU, vol. 3, pp. 5-8 (in Russian).

3.      Arbeev K.G. (1998) [Algorithm of construction of optimal orthogonal system of contingent claims]. In: Andreev A.S. (Ed.) “Fundamental Problems in Mathematics and Mechanics.” Ulyanovsk: ULGU, vol. 5 (1), pp. 13-18 (in Russian).

4.      Arbeev K.G. (1999) [Limit theorems for parameter estimators in systems of equations of diffusion type]. In: Romankov V.A. (Ed.) “Combinatorial and computing methods in mathematics.” Omsk: OmGU, pp. 35-51 (in Russian).

5.      Arbeev K.G. (1999) [One mathematical model of Russian financial market]. In: Andreev A.S. (Ed.) “Fundamental Problems in Mathematics and Mechanics.” Ulyanovsk: ULGU, vol. 6 (1), pp. 18-23 (in Russian).

6.      Butov A.A., Arbeev K.G., Jdanov D.A., Volkov M.A., Nosova A.E. (2000) [Stochastic model of metabolism based on separation of protein and carbohydrate food components]. Bulletin of Ulyanovsk State Technical University 3: 15-17 (in Russian). N.B.: table of contents of the journal is available online, see http://old.ulstu.ru/vestnik/num0003.html

7.      Yashin A.I., Ukraintseva S.V., De Benedictis G., Anisimov V.N., Butov A.A., Arbeev K.G., Jdanov D.A., Boiko S.I., Begun A.Z., Bonafe M., Franceschi C. (2001) Have the oldest old adults ever been frail in the past? A hypothesis that explains modern trends in survival. Journal of Gerontology: Biological Sciences 56A (10): B432-B442.

8.      Yashin A.I., Ukraintseva S.V., Boiko S.I., Arbeev K.G. (2002) Individual aging and mortality rate: How are they related? Social Biology 49 (3-4): 206-217.

9.      Anisimov V.N., Arbeev K.G., Popovich I.G., Zabezhinksi M.A., Rosenfeld S.V., Piskunova T.S., Arbeeva L.S., Semenchenko A.V., Yashin A.I. (2004) Body weight is not always a good predictor of longevity in mice. Experimental Gerontology 39 (3): 305–319.

10.  Arbeev K.G., Butov A.A., Manton K.G., Sannikov I.A., Yashin A.I. (2004) Disability trends in gender and race groups of early retirement ages in USA. Social and Preventive Medicine 49 (2): 142-151.

11.  Anisimov V.N., Arbeev K.G., Popovich I.G., Zabezhinksi M.A., Arbeeva L.S., Yashin A.I. (2004) Is early life body weight a predictor of longevity and tumor risk in rats? Experimental Gerontology 39 (5): 807-816.

12.  Ukraintseva S.V., Arbeev K.G., Michalsky A.I., Yashin A.I. (2004) Antiaging treatments have been legally prescribed for approximately thirty years. Annals of the New York Academy of Sciences 1019: 64-69.

13.  Arbeev K.G., Ukraintseva S.V., Arbeeva L.S., Yashin A.I. (2005) Mathematical models for human cancer incidence rates. Demographic Research 12: 237-272.

14.  Arbeev K.G., Ukraintseva S.V., Arbeeva L.S., Yashin A.I. (2005) Decline in human cancer incidence rates at old ages: Age-period-cohort considerations. Demographic Research 12: 273-300.

15.  Wienke A., Arbeev K.G., Locatelli I., Yashin A.I. (2005) A comparison of different bivariate correlated frailty models and estimation strategies. Mathematical Biosciences 198: 1-13.

16.  Arbeev K.G., Ukraintseva S.V., Arbeeva L.S., Yashin A.I. (2006) Difference between male and female cancer incidence rates: How can it be explained? In: Nikulin M., Commenges D., Huber C. (Eds.) “Probability, Statistics and Modelling in Public Health.” Springer-Verlag: New York, pp. 12-22.

17.  Weisman N.Ya., Arbeev K.G., Golubovsky M.D. (2006) [A decrease in the dose of the lgl tumor suppressor increases life span of Drosophila in stress and is related to the maternal effect]. Doklady Akademii Nauk 406 (1): 134-138 (in Russian).

18.  Weisman N.Ya., Arbeev K.G., Golubovsky M.D. (2006) A decrease in the dose of the lgl tumor suppressor increases life span of Drosophila in stress and is related to the maternal effect. Doklady Biological Sciences 406: 37-40.

19.  Ukraintseva S., Sloan F., Arbeev K., Yashin A. (2006) Increasing rates of dementia at time of declining mortality from stroke. Stroke 37 (5): 1155-1159.

20.  Golubovsky M.D., Weisman N.Y., Arbeev K.G., Ukraintseva S.V., Yashin A.I. (2006) Decrease in the lgl tumor suppressor dose in Drosophila increases survival and longevity in stress conditions. Experimental Gerontology 41 (9): 819-827.

21.  Kulminski A., Yashin A., Ukraintseva S., Akushevich I., Arbeev K., Land K., Manton K. (2006) Accumulation of health disorders as a systemic measure of aging: Findings from the NLTCS data. Mechanisms of Ageing and Development 127 (11): 840–848.

22.  Yashin A.I., Akushevich I.V., Arbeev K.G., Akushevich L., Ukraintseva S.V., Kulminski A. (2006) Insights on aging and exceptional longevity from longitudinal data: Novel findings from the Framingham Heart Study. AGE 28 (4): 363-374.

23.  Kulminski A., Yashin A., Arbeev K., Akushevich I., Ukraintseva S., Land K., Manton K. (2007) Cumulative index of health disorders as an indicator of aging-associated processes in the elderly: Results from analyses of the National Long Term Care Survey. Mechanisms of Ageing and Development 128 (3): 250–258.

24.  Yashin A.I., Arbeev K.G., Kulminski A., Akushevich I., Akushevich L., Ukraintseva S.V. (2007) Cumulative index of elderly disorders and its dynamic contribution to mortality and longevity. Rejuvenation Research 10 (1): 75-86.

25.  Yashin A.I., Arbeev K.G., Ukraintseva S.V. (2007) The accuracy of statistical estimates in genetic studies of aging can be significantly improved. Biogerontology 8 (3): 243-255.

26.  Yashin A.I., Arbeev K.G., Kulminski A., Akushevich I., Akushevich L., Ukraintseva S.V. (2007) Health decline, aging and mortality: How are they related? Biogerontology 8 (3): 291-302.

27.  Kulminski A.M., Ukraintseva S.V., Akushevich I.V., Arbeev K.G., Yashin A.I. (2007) Cumulative index of health deficiencies as a characteristic of long life. Journal of the American Geriatrics Society 55 (6): 935–940.

28.  Yashin A.I., Arbeev K.G., Akushevich I., Kulminski A., Akushevich L., Ukraintseva S.V. (2007) Stochastic model for analysis of longitudinal data on aging and mortality. Mathematical Biosciences 208 (2): 538-551.

29.  Kulminski A., Ukraintseva S.V., Akushevich I., Arbeev K.G., Land K., Yashin A.I. (2007) Accelerated accumulation of health deficits as a characteristic of aging. Experimental Gerontology 42 (10): 963-970.

30.  Ukraintseva S.V., Arbeev K.G., Yashin A.I. (2008) Chapter 5: Epidemiology of hormone-associated cancers as a reflection of age. In: Berstein L.M., Santen R.J. (Eds.) “Innovative Endocrinology of Cancer.” Springer series: Advances in Experimental Medicine and Biology, Volume 630. Landes Bioscience/Springer: New York, pp. 57-71. See chapter online at

http://www.eurekah.com/chapter/3530

31.  Kulminski A.M., Arbeev K.G., Kulminskaya I.V., Ukraintseva S.V., Land K., Akushevich I., Yashin A.I. (2008) Body mass index and nine-year mortality in disabled and nondisabled older U.S. individuals. Journal of the American Geriatrics Society 56 (1): 105-110.

32.  Yashin A.I., Arbeev K.G., Akushevich I., Kulminski A., Akushevich L., Ukraintseva S.V. (2008) Model of hidden heterogeneity in longitudinal data. Theoretical Population Biology 73 (1): 1-10.

33.  Kulminski A.M., Ukraintseva S.V., Arbeev K.G., Manton K.G., Oshima J., Martin G.M., Il'yasova D., Yashin A.I. (2008) Health-protective and adverse effects of the Apolipoprotein E e2 allele in older men. Journal of the American Geriatrics Society 56 (3): 478-483.

34.  Yashin A.I., Arbeev K.G., Kulminski A., Akushevich I., Akushevich L., Ukraintseva S.V. (2008) What age trajectories of cumulative deficits and medical costs tell us about individual aging and mortality risk: Findings from the NLTCS-Medicare data. Mechanisms of Aging and Development 129 (4): 191-200.

35.  Kulminski A.M., Ukraintseva S.V., Kulminskaya I.V., Arbeev K.G., Land K., Yashin A.I. (2008) Cumulative deficits better characterize susceptibility to death in elderly people than phenotypic frailty: Lessons from the Cardiovascular Health Study. Journal of the American Geriatrics Society 56 (5): 898-903.

36.  Kulminski A., Ukraintseva S.V., Arbeev K.G., Manton K.G., Oshima J., Martin G.M., Yashin A.I. (2008) Association between APOE e2/e3/e4 polymorphism and disability severity in a national long term care survey sample. Age and Ageing 37 (3): 288–293.

37.  Kulminski A.M., Arbeev K.G., Ukraintseva S.V., Culminskaya I.V., Land K., Yashin A.I. (2008) Changes in health status among participants of the Framingham Heart Study from the 1960s to the 1990s: Application of an index of cumulative deficits. Annals of Epidemiology 18 (9): 696-701.

38.  Kulminski A.M., Ukraintseva S.V., Culminskaya I.V., Arbeev K.G., Land K.C., Akushevich L., Yashin A.I. (2008) Cumulative deficits and physiological indices as predictors of mortality and long life. Journal of Gerontology: Biological Sciences 63A (10): 1053-1059.

39.  Kulminski A.M., Culminskaya I.V., Ukraintseva S.V., Arbeev K.G., Land K.C., Yashin A.I. (2008) Sex-specific health deterioration and mortality: the morbidity-mortality paradox over age and time. Experimental Gerontology 43 (12): 1052-1057.

40.  Yashin A.I., Ukraintseva S.V., Akushevich I.V., Arbeev K.G., Kulminski A., Akushevich L. (2009) Trade-off between cancer and aging: What role do other diseases play? Evidence from experimental and human population studies. Mechanisms of Ageing and Development 130 (1-2): 98-104.

41.  Kulminski A.M., Arbeev K.G., Culminskaya I.V., Ukraintseva S.V., Christensen K., Yashin A.I. (2009) Health-related phenotypes and longevity in Danish twins. Journal of Gerontology: Biological Sciences 64A (1): 1-8.

42.  Yashin A.I., Akushevich I., Arbeev K., Akushevich L., Kulminski A., Ukraintseva S. (2009) Studying health histories of cancer: A new model connecting cancer incidence and survival. Mathematical Biosciences 218 (2): 88-97.

43.  Arbeev K.G., Akushevich I., Kulminski A.M., Arbeeva L.S., Akushevich L., Ukraintseva S.V., Culminskaya I.V., Yashin A.I. (2009) Genetic model for longitudinal studies of aging, health, and longevity and its potential application to incomplete data. Journal of Theoretical Biology 258 (1): 103-111.

 

PRESENTATIONS:

1.      Arbeev K.G. (1998) [Limit theorems for parameter estimations in systems of diffusion type equations]. International Conference on Combinatorial and Computing Methods in Mathematics, Omsk, Russia, August 28-31, 1998 (poster). Paper is published in: Romankov V.A. (Ed.) (1999) “Combinatorial and computing methods in mathematics.” Omsk: OmGU, pp. 35-51 (in Russian).

2.      Arbeev K.G. (1998) [On the problem of optimal strategy in construction of assets portfolios]. 5th All-Russian Colloquium-School on Stochastic Methods, Yoshkar-Ola, Russia, December 6-12, 1998 (talk). See abstract in Review of Applied and Industrial Mathematics 5 (2): 196-197 (in Russian).

3.      Arbeev K.G., Butov A.A., Jdanov D.A. (2000) A stochastic approach in modeling and investigation of hormesis. 2nd European Congress on Biogerontology, St. Petersburg, Russia, August 25-28, 2000 (poster). See abstract in Advances in Gerontology 5: 32-33. See abstract online at

http://www.gerontology.ru/posters1.html#68

4.      Arbeev K.G., Butov A.A., Jdanov D.A. (2000) [Estimations of ruin probabilities in models of insurance upon "heavy losses"]. 7th All-Russian Colloquium-School on Stochastic Methods, Tuapse-Sochi, Russia, October 1-6, 2000 (poster). See abstract in Review of Applied and Industrial Mathematics 7 (2): 470 (in Russian). N.B.: table of contents is available online, see

http://www.tvp.ru/ourizd/oppm2000.htm#t7v2

5.      Yashin A.I., Ukraintseva S.V., Arbeev K.G., Boiko S.I. (2002) How can age patterns of cancer incidence and mortality rates be explained? Population Association of America 2002 Annual Meeting, Atlanta, GA, USA, May 9-11, 2002 (talk). See abstract online at

http://paa2002.princeton.edu/abstractViewer.asp?submissionId=60855

6.      Ukraintseva S.V., Yashin A.I., Arbeev K.G (2002) Cancer and aging in the light of recent findings from epidemiological and experimental biological studies. 3rd European Congress of Biogerontology, Florence, Italy, November 8-11, 2002 (poster). See abstract in Biogerontology 3 (Suppl. 1): 115-116.

7.      Yashin A.I., Wienke A., Arbeev K.G., Boiko S.I., Semenchenko A., Ukraintseva S.V. (2003) Survival models in aging studies of biological systems. International Conference on Reliability and Survival Analysis (ICRSA2003), Columbia, SC, USA, May 21-24, 2003 (talk). See abstract online at

http://www.stat.sc.edu/~pena/ICRSAWebsite/icrsa2003abstractbook.pdf (p. 55)

8.      Ukraintseva S.V., Arbeev K.G., Michalsky A.I., Yashin A.I. (2003) Anti-aging treatments have been legally prescribed since about 30 years. International Association of Biomedical Gerontology 10th Congress (IABG 10), Queens’ College, Cambridge, England, September 19-23, 2003 (poster). See abstract in: Ukraintseva S.V., Arbeev K.G., Michalsky A.I., Yashin A.I. (2003) For about 30 years anti-aging treatments have been legally prescribed. Biogerontology 4 (Suppl. 1): 96.

9.      Arbeev K.G., Michalski A.I., Ukraintseva S.V., Yashin A.I. (2004) Relationship between disability and risk of death at advanced ages: Results from the NLTCS. Biodemography of Survival and Longevity Meeting, Duke University, Durham, NC, USA, March 11-13, 2004 (talk).

10.  Arbeev K.G., Semenchenko A.V., Anisimov V.N., Ukraintseva S.V., Arbeeva L.S., Yashin A.I. (2004) Relationship between cancer and aging: Experimental evidence and mathematical modeling considerations. Population Association of America 2004 Annual Meeting, Boston, MA, USA, April 1-3, 2004 (poster). See abstract online at

http://paa2004.princeton.edu/abstractViewer.asp?submissionId=40092

11.  Yashin A.I., Michalski A.I., Ukraintseva S.V., Arbeev K.G. (2004) Morbidity, disability and longevity: In search of connection. The National Long Term Care Survey – Spotlight on Research, Fall Conference, Washington, DC, USA, November 22, 2004 (talk).

12.  Yashin A.I., Martin G.M., Arbeev K.G., Oshima J., Ukraintseva S.V., Huang H., Hanson E. (2004) Genetics of health and disability from NLTCS data: Effects of APOE alleles. The National Long Term Care Survey – Spotlight on Research, Fall Conference, Washington, DC, USA, November 22, 2004 (talk).

13.  Yashin A.I., Ukraintseva S.V., Arbeev K.G., Huang H., Hanson E. (2005) Genetics of aging, health, disability and longevity: A statistical modeling perspective. Population Association of America 2005 Annual Meeting, Philadelphia, PA, USA, March 31 – April 2, 2005 (talk). See abstract online at http://paa2005.princeton.edu/abstractViewer.aspx?submissionId=50705

14.  Yashin A.I., Akushevich I., Arbeev K.G., Kulminski A., Ukraintseva S.V. (2005) Mathematical models for biodemographic applications: Advantages and limitations of longitudinal data. Workshop on Mathematical and Statistical Models in the Biodemography of Aging, Berkeley, CA, USA, June 6-8, 2005 (talk). See abstract online at

http://www.demog.berkeley.edu/~dstein/modeling/yashinabs.rtf

15.  Golubovski M.D., Weisman N.Y., Arbeev K.G., Ukraintseva S.V., Yashin A.I. (2005) Tumor suppressor mutants of Drosophila live longer in stressful conditions and this effect is strengthened by epigenetic inheritance from mothers. Environmental Epigenomics, Imprinting and Disease Susceptibility (poster). Duke University/NIEHS conference, Durham, NC, USA, November 2-4, 2005.

16.  Michalski A.I., Ukraintseva S.V., Arbeev K.G., Yashin A.I. (2005) Investigation of old age mortality structure in the presence of co-morbidity. European Conference on Chronic Disease Prevention (Learning From the Past – Planning for the Future), Helsinki, Finland, December 8-10, 2005 (poster). See abstract online at

http://www.ktl.fi/attachments/suomi/julkaisut/julkaisusarja_b/2005/2005b21.pdf (p. 60)

17.  Ukraintseva S.V., Arbeev K.G., Yashin A.I. (2006) Factors favoring both longevity and cancer risk in developed countries. Cancer and the Environment Conference at Duke. Environmental Sentinels for Human Disease (poster). Durham, NC, USA, March 30-31, 2006.

18.  Kulminski A., Akushevich I., Land K., Arbeev K.G. (2006) Cumulative index of age-associated health disorders as a major indicator of aging processes and mortality risks in elderly populations: Results from analyses of the National Long-Term Care Survey. Population Association of America 2006 Annual Meeting, Los Angeles, CA, USA, March 30 – April 1, 2006 (talk). See paper online at http://paa2006.princeton.edu/download.aspx?submissionId=60708

19.  Yashin A.I., Akushevich I.V., Arbeev K.G., Akushevich L., Ukraintseva S.V. (2006) The secrets of long life from longitudinal data. Population Association of America 2006 Annual Meeting, Los Angeles, CA, USA, March 30 – April 1, 2006 (talk). See abstract online at

http://paa2006.princeton.edu/abstractViewer.aspx?submissionId=60392

20.  Ukraintseva S., Golubovsky M., Weisman N., Arbeev K., Yashin A. (2006) Drosophilas deficient in tumor suppressor survive better stressful conditions: possible involvement of apoptosis. The 35th American Aging Association Annual Meeting “Interventions in Aging and Age-related Disease: The Present and Future,” Boston, MA, USA, June 2-5, 2006 (poster). See abstract in AGE 28 (1): 67-68.

21.  Yashin A.I., Arbeev K.G., Kulminski A., Akushevich I., Akushevich L., Ukraintseva S.V. (2006) Health decline, aging and mortality: How are they related? International Conference on “Statistical Latent Variables Models in the Health Sciences,” Perugia, Italy, September 6-8, 2006 (talk). See presentation online at http://www.stat.unipg.it/forcina/shlav/Thursday%207/Yashin.pdf

22.  Yashin A.I., Kovtun M., Akushevich I., Arbeev K.G. (2006) Consistency of parameter estimates in the GoM like latent structure models. In: Abstracts of the International Conference on “Statistical Latent Variables Models in the Health Sciences”, Perugia, Italy, September 6-8, 2006, pp. 115-118. See abstract online at http://www.stat.unipg.it/shlav/book.pdf

23.  Yashin A., Arbeev K., Ukraintseva S. (2006) Combining genetic and non-genetic data improves the quality of conclusions in genetic studies of aging and longevity. The Gerontological Society of America’s 59th Annual Scientific Meeting, Dallas, TX, USA, November 16-20, 2006 (poster). See abstract in The Gerontologist 46 (Sp. Iss. 1): 137.

24.  Arbeev K., Kulminski A., Ukraintseva S., Yashin A., Akushevich I., Akushevich L. (2006) Evaluating effects of senescence from longitudinal data: Statistical modeling perspective. The Gerontological Society of America’s 59th Annual Scientific Meeting, Dallas, TX, USA, November 16-20, 2006 (talk). See abstract in The Gerontologist 46 (Sp. Iss. 1): 380.

25.  Kulminski A., Yashin A., Ukraintseva S., Arbeev K., Land K., Akushevich I. (2006) Accumulation of health disorders as a determinant of physiological aging. The Gerontological Society of America’s 59th Annual Scientific Meeting, Dallas, TX, USA, November 16-20, 2006 (talk). See abstract in The Gerontologist 46 (Sp. Iss. 1): 565.

26.  Yashin A., Akushevich I., Arbeev K., Akushevich L., Kulminski A., Ukraintseva S. (2006) Evaluating effects of senescence on risks of disease and death: Statistical modeling perspective. The Gerontological Society of America’s 59th Annual Scientific Meeting, Dallas, TX, USA, November 16-20, 2006 (poster). See abstract in The Gerontologist 46 (Sp. Iss. 1): 518-519.

27.  Ukraintseva S.V., Arbeev K.G., Yashin A.I. (2007) Factors favoring both cancer risk and longevity in developed countries. Translational Research at the Aging and Cancer Interface. AACR Conference, San-Diego, CA, USA, February 20-23, 2007 (poster). See abstract online at

http://www.aacr.org/eServices/ABS_GLOB/abs_body.asp?ABSID=5883

28.  Akushevich I., Veremeeva G., Yashin A., Manton K.G., Kulminski A., Kovtun M., Kravchenko J., Akleev A.V., Ukraintseva S., Akushevich L., Arbeev K. (2007) New perspectives in modeling of IR induced carcinogenesis. North Carolina Health Physics Society spring 2007 Meeting, Charlotte, NC, USA, February 22-23, 2007 (talk). See presentation online at

 http://hpschapters.org/northcarolina/spring2007/report_NCHPS_2007-Akusevich.pdf

29.  Yashin A.I., Arbeev K.G., Akushevich I., Kulminski A., Akushevich L., Ukraintseva S.V. (2007) Connecting fundamental concepts of human aging: A statistical modeling perspective. Population Association of America 2007 Annual Meeting, New York, NY, USA, March 29-31, 2007 (talk). See paper online at

http://paa2007.princeton.edu/download.aspx?submissionId=70979

30.  Kulminski A., Ukraintseva S.V., Akushevich I., Arbeev K.G., Yashin A.I. (2007) Cumulative index of health disorders and longevity. Population Association of America 2007 Annual Meeting, New York, NY, USA, March 29-31, 2007 (talk). See paper online at

http://paa2007.princeton.edu/download.aspx?submissionId=70587

31.  Yashin A.I., Arbeev K.G., Akushevich I., Akushevich L., Kulminski A., Ukraintseva S.V. (2007) Incorporating fundamental properties of ageing to models of longitudinal data. VI European Congress of the International Association of Gerontology and Geriatrics, Saint-Petersburg, Russia, July 5-8, 2007 (talk). See abstract in Advances in Gerontology 20 (3): 323.

32.  Akushevich I., Veremeeva G., Kulminski A., Ukraintseva S., Arbeev K., Akleyev A.V., Yashin A. (2007) New perspectives in modeling of carcinogenesis induced by ionizing radiation. The 13th International Congress of Radiation Research (ICRR 2007), San Francisco, CA, USA, July 8-12, 2007 (poster). See abstract in The 13th International Congress of Radiation Research. Abstract Book: p. 246. The abstract book is available online at

http://171.65.6.67/icrr2007/documents/abstracts_author_index.pdf

33.  Yashin A.I., Ukraintseva S.V., Akushevich I., Arbeev K.G., Kulminski A., Akushevich L. (2007) Biodemography of cancer and aging: Statistical modeling perspective. SENECA 2007 European Conference on Cancer and Ageing, Warsaw, Poland, October 4-6, 2007 (talk). See abstract in Acta Biochimica Polonica 54 (Suppl. 5): 2.

34.  Yashin A.I., Arbeev K.G., Ukraintseva S.V., Kulminski A., Akushevich I., Akushevich L. (2007) Studying Aging, Health and Longevity from Longitudinal Data. The 5th Annual National Academies Keck Futures Initiative Conference “The Future of Human Healthspan: Demography, Evolution, Medicine, and Bioengineering,” Irvine, CA, USA, November 14-16, 2007 (poster). See web site of the conference:

http://www.keckfutures.org/site/PageServer?pagename=Upcoming_Aging_Conference_Nov_2007

35.  Kulminski A., Ukraintseva S., Arbeev K., Yashin A. (2007) Dualism of the Apolipoprotein 2 genetic variants in older males. The Gerontological Society of America’s 60th Annual Scientific Meeting, San Francisco, CA, USA, November 16-20, 2007 (talk). Abstract is published in The Gerontologist 47 (Sp. Iss. 1): 644-645. See abstract online at

http://www.agingconference.com/e_pop_profiles.cfm?session=1&child=1&session_id=85260&class_id=84178&abstract=1

36.  Kulminski A., Ukraintseva S., Arbeev K., Yashin A. (2007) Is the Apolipoprotein e2 allele protective of health in aging males? The Gerontological Society of America’s 60th Annual Scientific Meeting, San Francisco, CA, USA, November 16-20, 2007 (poster). Abstract is published in The Gerontologist 47 (Sp. Iss. 1): 277. See abstract online at

http://www.agingconference.com/e_pop_profiles.cfm?session=1&child=1&session_id=88577&class_id=83961&abstract=1

37.  Yashin A.I., Arbeev K.G., Akushevich I., Kulminski A., Akushevich L., Ukraintseva S.V. (2007) What longitudinal data tell us about aging and life span determination. The Gerontological Society of America’s 60th Annual Scientific Meeting, San Francisco, CA, USA, November 16-20, 2007 (talk). Abstract is published in The Gerontologist 47 (Sp. Iss. 1): 645. See abstract online at

http://www.agingconference.com/e_pop_profiles.cfm?session=1&child=1&session_id=85259&class_id=84180&abstract=1

38.  Yashin A.I., Arbeev K.G., Akushevich I., Kulminski A., Akushevich L., Ukraintseva S.V. (2007) Dynamic connection between aging related health decline, medical cost and mortality. The Gerontological Society of America’s 60th Annual Scientific Meeting, San Francisco, CA, USA, November 16-20, 2007 (poster). Abstract is published in The Gerontologist 47 (Sp. Iss. 1): 296-297. See abstract online at

http://www.agingconference.com/e_pop_profiles.cfm?session=1&child=1&session_id=88494&class_id=82355&abstract=1

39.  Yashin A.I., Arbeev K.G., Ukraintseva S.V., Kulminski A., Akushevich I., Akushevich L. (2007) Redefining physiological norms to minimize mortality risk in the elderly. The Gerontological Society of America’s 60th Annual Scientific Meeting, San Francisco, CA, USA, November 16-20, 2007 (talk). Abstract is published in The Gerontologist 47 (Sp. Iss. 1): 402. See abstract online at

http://www.agingconference.com/e_pop_profiles.cfm?session=1&child=1&session_id=85538&class_id=84739&abstract=1

40.  Kulminski A.M., Arbeev K.G., Ukraintseva S.V., Kulminskaya I.V., Akushevich I. (2008) Changes in health among the participants of the Framingham Heart Study from 1960s to 1990s: Application for an index of cumulative deficits. Population Association of America 2008 Annual Meeting, New Orleans, LA, USA, April 17-19, 2008 (talk). See paper online at

http://paa2008.princeton.edu/download.aspx?submissionId=80345

41.  Yashin A.I., Arbeev K.G., Akushevich I., Akushevich L. (2008) Model of hidden heterogeneity in longitudinal data. Population Association of America 2008 Annual Meeting, New Orleans, LA, USA, April 17-19, 2008 (talk). See paper online at http://paa2008.princeton.edu/download.aspx?submissionId=81491

42.  Yashin A.I., Arbeev K.G., Akushevich I.V., Kulminski A., Akushevich L., Culminskaya I., Arbeeva L., Ukraintseva S.V. (2008) Age trajectories of physiological state and factors affecting them: What do they tell us about aging and longevity? American Aging Association – 37th Annual Meeting “The Role of Genes, Environment and Chance in Determining Aging,” Boulder, CO, USA, May 30 - June 2, 2008 (talk).

43.  Yashin A.I., Ukraintseva S.V., Arbeev K.G., Culminskaya I.V., Akushevich I., Kulminski A. (2008) Trade-off effects of ACE D/I polymorphism on disease risks, physiological indices, and survival. American Aging Association – 37th Annual Meeting “The Role of Genes, Environment and Chance in Determining Aging,” Boulder, CO, USA, May 30 - June 2, 2008 (poster).

44.  Yashin A.I., Ukraintseva S.V., Arbeev K.G., Culminskaya I.V., Akushevich I.V., Kulminski A. (2008) Effects of APOE e2/e3/e4 polymorphism suggest trade-offs between risk factors for CVD. American Aging Association – 37th Annual Meeting “The Role of Genes, Environment and Chance in Determining Aging,” Boulder, CO, USA, May 30 - June 2, 2008 (poster).

45.  Kulminski A.M., Arbeev K.G., Ukraintseva S.V., Culminskaya I.V., Land K., Yashin A.I. (2008) Changes in health deterioration among participants of the Framingham Heart Study from the 1960s to the 1990s. The 2008 European Population Conference, Barcelona, Spain, July 9-12, 2008 (poster). See paper online at: http://epc2008.princeton.edu/download.aspx?submissionId=80784

46.  Akushevich I., Veremeyeva G., Ukraintseva S., Arbeev K., Akleyev A.V., Yashin A.I. (2008) A new model of short- and long-term effects of exposure to ionizing radiation in hematopoietic system of humans. The 36th Annual Meeting of the European Radiation Research Society, Tours, France, September 1-4, 2008 (poster). Abstract published in Radioprotection 43 (5): 90-91.

47.  Arbeev K.G., Yashin A.I., Akushevich I., Kulminski A.M., Arbeeva L.S., Akushevich L., Ukraintseva S.V. (2008) Stochastic model for joint analysis of genetic and non-genetic data from longitudinal studies of aging, health and longevity. IGES 2008: The 17th Annual Meeting of the International Genetic Epidemiology Society (IGES), St. Louis, Missouri, USA, September 15-16, 2008 (poster). Abstract is published in Genetic Epidemiology 32 (7): 678-678.

48.  Matteini A.M., Fallin M.D., Kammerer C.M., Schupf N., Yashin A.I., Mayeux R., Arbeev K.G., Hadley E.C., Newman A.B., Walston J.D. (2008) Endophenotypes of pulmonary and physical function are heritable in the Long Life Family Study. IGES 2008: The 17th Annual Meeting of the International Genetic Epidemiology Society (IGES), St. Louis, Missouri, USA, September 15-16, 2008 (poster). Abstract is published in Genetic Epidemiology 32 (7): 706-707.

49.  Yashin A.I., Culminskaya I.V., Arbeev K.G., Ukraintseva S.V., Akushevich I., Kulminski A. (2008) Effects of ACE D/I polymorphism and 11 SNPs heterozygosity in the same gene on health risks in Framingham Study. IGES 2008: The 17th Annual Meeting of the International Genetic Epidemiology Society (IGES), St. Louis, Missouri, USA, September 15-16, 2008 (poster). Abstract is published in Genetic Epidemiology 32 (7): 722-722.

50.  Yashin A.I., Ukraintseva S.V., Arbeev K.G., Culminskaya I.V., Akushevich I., Kulminski A. (2008) Interacting effects of ACE D/I polymorphism and smoking on health risks in Framingham Study. IGES 2008: The 17th Annual Meeting of the International Genetic Epidemiology Society (IGES), St. Louis, Missouri, USA, September 15-16, 2008 (poster). Abstract is published in Genetic Epidemiology 32 (7): 722-723.

51.  Akushevich I., Veremeyeva G., Ukraintseva S., Arbeev K., Akleyev A.V., Yashin A.I. (2008) A new stochastic model of carcinogenesis induced by ionizing radiation and the concept of breaking barrier cell mechanisms. The 12th International Congress of the International Radiation Protection Association, Buenos Aires, Argentina, October 19-24, 2008 (poster).

52.  Akushevich I., Akushevich L., Kravchenko J., Ukraintseva S., Arbeev K., Yashin A.I. (2008) Place of behavior risk factors in cancer risk of the U.S. elderly population. 7th Annual AACR International Conference on Frontiers in Cancer Prevention Research, National Harbor, MD, USA, November 16-19, 2008 (poster).

53.  Yashin A.I., Akushevich I., Arbeev K., Akushevich L., Kulminski A., Ukraintseva S. (2008) Capturing connection between aging and aging-associated diseases: The case of cancer. 7th Annual AACR International Conference on Frontiers in Cancer Prevention Research, National Harbor, MD, USA, November 16-19, 2008 (poster).

54.  Ukraintseva S., Arbeev K., Akushevich I., Kulminski A., Yashin A. (2008) Dependencies between cancer and other major disorders of the elderly. 7th Annual AACR International Conference on Frontiers in Cancer Prevention Research, National Harbor, MD, USA, November 16-19, 2008 (poster).

55.  Arbeev K.G., Ukraintseva S.V., Akushevich I., Kulminski A.M., Arbeeva L.S., Akushevich L., Culminskaya I.V., Yashin A.I. (2008) Trade-off between cancer and aging: inferences from experimental and human population studies. Amazon Project, the 7th Biennial International Conference, Palermo, Italy, November 17-22, 2008 (talk, invited speaker).

56.  Kulminski A., Ukraintseva S., Culminskaya I., Arbeev K., Land K.,  Akushevich L., Yashin A. (2008) Cumulative deficit indices better predict mortality and long life then physiological risk factors. 61st Annual Scientific Meeting of the Gerontological Society of America “Resilience in an Aging Society: Risks and Opportunities,” National Harbor, MD, USA, November 21-25, 2008 (talk).

57.  Kulminski A.M., Culminskaya I., Ukraintseva S., Arbeev K., Land K., Yashin A. (2008) Gender-Specific Health Deterioration and Mortality: The Morbidity-Mortality Paradox over Age and Time. 61st Annual Scientific Meeting of the Gerontological Society of America “Resilience in an Aging Society: Risks and Opportunities,” National Harbor, MD, USA, November 21-25, 2008 (talk). Abstract is published in The Gerontologist 48 (Sp. Iss. 3): 544.

58.  Yashin A., Arbeev K., Kulminski A., Christensen K., Borecki I., Lee J., Elo I., Terry L., Hadley E., Rossi W., Cheng R. (2008) Predicting parental longevity from offspring endophenotypes using data from the Long Life Family Study. 61st Annual Scientific Meeting of the Gerontological Society of America “Resilience in an Aging Society: Risks and Opportunities,” National Harbor, MD, USA, November 21-25, 2008 (poster). Abstract is published in The Gerontologist 48 (Sp. Iss. 3): 492-493.

59.  Yashin A., Ukraintseva S., Arbeev K., Akushevich I., Culminskaya I., Kulminski A. (2008) Capturing systemic aspects of aging related changes in human: from data to model. 61st Annual Scientific Meeting of the Gerontological Society of America “Resilience in an Aging Society: Risks and Opportunities,” National Harbor, MD, USA, November 21-25, 2008 (talk). Abstract is published in The Gerontologist 48 (Sp. Iss. 3): 161.

60.  Yashin A.I., Arbeev K.G., Akushevich I., Ukraintseva S.V., Culminskaya I.V., Kulminski A. (2009) Trajectories of physiological aging and their role in health and longevity: the case of Framingham data. Gordon Research Conference on Biology of Aging, Ventura, CA, USA, February 15-20, 2009 (poster).

61.  Ukraintseva S., Arbeev K., Akushevich I., Kulminski A., Yashin A. (2009) Trade-offs between cancer and other diseases: Role in aging and longevity. Molecular Mechanisms of Aging and Age-Related Diseases (Second International Neurodegeneration Meeting). Puerto Vallarta, Mexico, March 3-6, 2009 (poster).

62.  Yashin A.I., Ukraintseva S.V., Arbeev K.G., Kulminski A., Arbeeva L., Culminskaya I.V. (2009) Biodemography of exceptional survival: Lessons from longitudinal data. Population Association of America 2009 Annual Meeting, Detroit, MI, USA, April 30 – May 2, 2009 (talk). See paper online at http://paa2009.princeton.edu/download.aspx?submissionId=91428

63.  Arbeev K.G., Arbeeva L., Ukraintseva S.V., Culminskaya I.V. (2009) Genetic model for longitudinal studies of aging, health, and longevity and its application to Framingham Heart Study data. Population Association of America 2009 Annual Meeting, Detroit, MI, USA, April 30 – May 2, 2009 (poster). See extended abstract online at

http://paa2009.princeton.edu/download.aspx?submissionId=91455

64.  Akushevich I., Veremeyeva G., Dimov G., Ukraintseva S., Arbeev K., Akleyev A.V., Yashin A.I. (2009) Modeling interrelation of short- and long-term health effects in hematopoietic system of humans chronically exposed to ionizing radiation. Late Health Effects of Ionizing Radiation: Bridging the Experimental and Epidemiologic Divide. Washington, DC, USA, May 4-6, 2009 (poster).

65.  Akushevich I., Veremeyeva G., Dimov G., Ukraintseva S., Arbeev K., Akleyev A.V., Yashin A.I. (2009) Modeling deterministic effects in hematopoietic system caused by chronic exposure to ionizing radiation in large human cohorts. 10th International Conference on the Health Effects of Incorporated Radionuclides (HEIR 2009). Santa Fe, NM, USA, May 10-14, 2009 (poster).

66.  Yashin A.I., Akushevich I., Ukraintseva S.V., Arbeev K.G., Kulminskaya I., Arbeeva L., Kulminski A. (2009) Aging, cancer, and other diseases: insights for improving population health and longevity. The 13th Congress of the International Association of Biomedical Gerontology (13th IABG) "Aging, cancer, and age-related diseases; common mechanisms?" Quebec City, Canada, May 18-20, 2009 (talk).

67.  Arbeev K.G., Akushevich I., Kulminski A.M., Yashin A.I. (2009) Mathematical model for investigation of aging-related processes in organisms using joint analysis of genetic and non-genetic data from longitudinal studies. The 6th International Conference on Mathematical Methods in Reliability (MMR 2009). Moscow, Russia, June 22-27, 2009 (talk).

68.  Ukraintseva S., Yashin A., Arbeev K., Akushevich I., Kulminski A. (2009) Trade-offs between major elderly disorders: impact on aging and longevity. The 19th IAGG (International Association of Gerontology and Geriatrics) World Congress of Gerontology and Geriatrics (IAGG 2009). Paris, France, July 5-9, 2009 (talk).

 

WORKING PAPERS AND PREPRINTS:

1.      Wienke A., Arbeev K.G., Locatelli I., Yashin A.I. (2003) A simulation study of different correlated frailty models and estimation strategies. MPIDR Working Paper Series, WP 2003-018, 22 pages. Available online at

http://www.demogr.mpg.de/papers/working/wp-2003-018.pdf.

2.      Kulminski A., Yashin A., Ukraintseva S., Akushevich I., Arbeev K., Land K., Manton K. (2005) Age-associated disorders as a proxy measure of biological age: Findings from the NLTCS data. Preprint # q-bio/0509034 published at Los-Alamos National Lab archive:

      http://arxiv.org/ftp/q-bio/papers/0509/0509034.pdf.

3.      Kulminski A., Yashin A., Akushevich I., Ukraintseva S., Land K., Arbeev K., Manton K. (2005) Frailty index as a major indicator of aging processes and mortality in elderly: Results from analyses of the National Long Term Care Survey data. Preprint # q-bio/0509038 published at Los-Alamos National Lab archive: http://arxiv.org/ftp/q-bio/papers/0509/0509038.pdf.